Nasal Spotlight

SESSION 7: Designing Intranasal Delivery Systems for Deposition, Retention, and Scale

Wednesday • May 13, 2026 • 1:30–3:00 PM • Trailblazer’s Ballroom
Moderator: Julie D. Suman, Ph.D.

Advancing Intranasal Drug Delivery: Insights into Regional Deposition across Age and Disease
Laleh Golshahi
Virginia Commonwealth University
A Quantitative Framework for Modulating Mucus Viscoelasticity to Extend Nasal Residence of Antiviral Proteins
Ashlee Brunaugh
University of Michigan
Designing Nasal Powders for Biologics: Formulation, Process Design and Manufacturability Considerations
Kimberly Shepard
Lonza

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Innovative Strategies in Nasal Powder Drug Delivery: Device Design, Advanced Formulations, and Analytical Approaches
Dina Morais and Claudia Costa
Hovione
From Droplets to Particles: Excipients Shaping Spray‑Dried Intranasal Powders
Sana Hosseini
Aptar Pharma
A Spray-Drying Framework for Intranasal Powders Across Multiple Sites and Dryer Scales
Sana Hosseini
Aptar Pharma
Human Factor Studies and Actuation Force in Multidose Nasal Pumps 
Goncalo Farias
Aptar Pharma
Evaluation of Regional Deposition in 3D Printed Infant Nasal Cast Models for Vaccination via Intranasal Delivery
Goncalo Farias
Aptar Pharma
Evaluation of Permeation Enhancers for Intranasal Delivery of Epinephrine and Naloxone Hydrochloride Using a 3D Nasal Tissue Model
Veronica Freitas Blanco
Croda
Advancing Nasal Powder Delivery: A Structured Evolution of Device Performance
Angelo Araujo and Claudia Costa
Hovione
Evaluation of β-lactoglobulin (Dispersome®) as a Novel Excipient for Pulmonary and Nasal Delivery
Claudia Costa
Hovione
Critical Quality Attribute-Driven Calu-3 Air-Liquid Interface Model for Comparative Permeability Screening of Dry Powder and Liquid Formulations  
Beatriz Gamelas and Dina Morais
Hovione
Preliminary Spray Drying Screening Study for the Reformulation of Ganaxolone from Oral to Nasal Delivery
Anna Vivani and Irene Rossi
INTO
The Case for Inhaled, Thermostable Powder Vaccines Against Respiratory Pathogens in Pandemic Readiness
Svetlana Lyapustina and Beatriz Noriega Fernandes
IPAC-RS
Tuning Nasal Spray Performance by Formulation Design
Rob McCorkle
Kindeva
Thermostable Powder-Based Nasal Vaccine: Preclinical Evaluation of Immunogenicity and Stability
Jonas Sävmarker
Orexo AB
Actuation and Viscosity Dependent Aerosol Generation in Nasal Sprays: A Mechanistic Comparison of Swirl Nozzle and Soft Mist Technologies
Nicolas Buchmann
Resyca
Adapting Standard Nasal Spray Testing Methodologies for Live BSL-2 Viral Products: An In-Use Case Study with a SARS-CoV-2 Nasal Vaccine
Yannick Baschung
Solvias
Numerical and Experimental Studies to Enhance Nasopharyngeal Deposition by Optimizing Spray Plume Angle and Particulate Sizes for Intranasal Drug Delivery
Joshua Reineke
South Dakota State University
Influence of Formulation Viscosity and Surface Tension on Spray Formation and Nasal Deposition with a VP7 Nasal Valve Device
Sorrel Haughton
University of Bristol
Nasal Delivery of Liquid Medicines: Effect of Viscosity and Polymer Structure on Delivery Performance
Hessam Rasooli Nia
University of Hertfordshire
Device Characteristics and Orientation Effects on Regional Nasal Drug Deposition in an Anatomical Nasal Model
Mohammad Hejazi
Virginia Commonwealth University
Effect of Breathing Pattern and Emitted Dose on Regional Deposition of Soft-Mist Nasal Sprays
Mohammad Hejazi
Virginia Commonwealth University
Bridging Deposition and Permeation: Evaluation of Intranasal Dry Powder Antiemetic Formulations
Patrick He
Woolcock Institute of Medical Research
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