Inspiring Dry Powder Inhalation

Inspiring Dry Powder Inhalation: Next Generation Carriers

Wednesday • May 7, 2025 • 11:00–12:00 Noon
Moderator: Paul Young, Ph.D., Macquarie University, Sydney, Australia

Carrier Size, Surface & Geometry: New Tools to Provide a Mechanistic Understanding of Interactive Powder Blends
Regina Scherließ
Kiel University
β-lactoglobulin (Dispersome®): A Novel Excipient for Enhancing the Aerosolization of Dry Powder Inhalation Products
Paulo Lino
Hovione

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Optimizing Biologics Powder Formulations: Achieving High Drug Load, Stability, and Efficient Inhalation
Luis Marques and Filipe Vultos
Hovione
A Systematic and Efficient Approach Through Use of Complimentary Expertise to Mitigate Uncertainty and Accelerate Dry Powder Inhaler Development
Irene Rossi, Ross Blezard and Andrea Silvestri
INTO
An Expanded Toolbox for Respirable Dry Powders: Pulmonary and Intranasal Delivery for Small and Biotherapeutic APIs
Beatriz Noriega Fernandes and Eric Peterson
Lonza
High Delivered Dose in a Single Inhalation for Carrier-Based Formulations by Retaining Carrier-Fraction in Dry Powder Inhaler Blister
Heather Jameson
Cambridge Healthcare Innovations
Formulation Study on siRNA-LNP Embedded in an Inhalable Freeze-Dried Matrix for Lung Targeting
Michael Vernizzi
Chiesi Farmaceutici
Further Exploration on the Manufacturing Repeatability and the Interaction Between Blending Parameters of Dry Powder Blends Produced by Resonant Acoustic Mixing
Cristina Rey Blanes
Chiesi Limited
Impact of Lactose Carrier Morphology and Amorphicity on the Aerosol Performance of Fluticasone Propionate Dry Powder Inhalers
Ross Blezard
DFE Pharma
Optimization of Carrier Particle Geometry for Enhanced Inhalation Performance by Parametric Design
Melvin Wostry
Kiel University
Fine-Tuning Spray-Dried Inhalable Powders: Impact of Component Saturation on Performance
Beatriz Noriega Fernandes and Emily Osborne
Lonza
Selection of the Best Capsule Type to Maximize the Performance of a Model Carrier-Based Dry Powder Inhalation Formulation
Camille Dumont
Lonza
The Role of Carrier Particle Size in Adhesive Mixtures for Inhalation
Kyrre Thalberg
Lund University
Predicting Blend Performance of a Dry Powder Inhalation Formulation Using Raman Spectroscopy
Vaishnavi Kapileshwari and Mridul Majumder
M2M Pharmaceuticals
The Impact of Excipients and Spray Drying on Improving the Permeability of Spray-Dried Leuprolide Formulations Using RPMI-2650 Cells
Lucas Silva
Nanopharm
The Impact of Orbital™ Device Puck Configurations on the Deposition of Itraconazole
Lucas Silva
Nanopharm
Simplified Mechanism Modelling: Optimizing a Dry Powder Inhaler for Ease of Use
Philip Smith
Phillips Medisize
The Influence of Freezing, Storage, and Formulation on Mannitol Polymorphism and Powder Deposition after Spray Freeze-Drying
Lorena Pasero
Politecnico di Torino
Spray Freeze-Drying Inhalable Powders of a Monoclonal Antibody: The Role of Formulation in Achieving Stability and Flowability
Lorena Pasero
Politecnico di Torino
Pre-Actuation Microstructure within Dry Powder Inhaler Blisters Revealed Through X-Ray Computed Tomography
Darragh Murnane
University of Hertfordshire
Development of a Dry Powder Formulation of Deoxyribonuclease I using Spray Drying
Aoife Cotter
University of Limerick
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