Testing True Product Performance
Leader in spray and aerosol product testing and contract services
Proveris® Scientific’s focus is helping its customers unlock the complex relationships between formulation, device, and human usage—knowledge that’s essential for timely and effective orally inhaled and nasal drug product (OINDP) development and commercialization. Our industry standard instruments offer rapid insight into critical spray and aerosol parameters, and our team of scientists provide expert consultation and contract test services, taking into account key regulatory and operational nuances of OINDPs.
As key partners to our clients we help to:
- accelerate successful product development and prevent late-stage development failures
- realize significant savings in time and resources by streamlining testing workflows
- evaluate the suitability of various OINDP delivery devices and optimize device parameters for maximum efficacy
- optimize testing variables to maintain batch-to-batch reproducibility, simplifying regulatory submissions
Proveris Scientific
2 Cabot Road
Hudson, MA 01749
USA
Testing Solutions
Proveris core platforms are used for spray and aerosol characterization, through-life testing, automated nasal spray collection for spraying & weighing, dose content uniformity, automated shaking & actuation for wasting of pMDIs. Powerful Viota® software is used to preserve the audit trail and efficiently manage data. More Info
Contract Test Services
Contract test services include customizable packaged studies for method development, formulation and device screening/optimization, human actuation studies, spray characterization, and for measuring regional drug deposition using physiologically relevant models. More Info
Spray Pattern and Plume Geometry
Various factors can affect the spray pattern and plume geometry, including the size and shape of the actuator orifice, the design of the actuator, the size of the metering chamber, the size of the stem orifice of the valve, the vapor pressure in the container, and the nature of the formulation. Understanding these effects becomes essential to successful drug development and approval. More Info
Automated Actuation
The ideal way to conduct testing of inhaled and intranasal drug products is automated, mechanical actuation using a defined testing profile derived from human-usage data. This approach reduces variability and is in line with patient-usage. It also makes it possible to avoid the inherent human error that arises due to operator fatigue and other influences when testing a high volume of samples. More Info
Services for Unit-Dose Nasal Spray Development
The development of a successful unit-dose nasal spray or powder is an intricate process that requires a thorough understanding of the interactions between formulation, device, and human-usage. Our focused expertise, tools, and methodologies provide insight and understanding for making informed decisions to accelerate product success. More Info