Posters on the Podium

Posters on the Podium

Monday • May 2, 2022 • 3:30–5:00 pm EDT • National Ballroom
Moderators: Daniela Traini, Macquarie University & Serena Bonasera, Virginia Commonwealth University
A Within-Host Modeling Framework for SARS-CoV-2 Infection to Support Intranasal Vaccine Strategies
Jeffry Schroeter
Applied Research Associates
In Vitro Regional Deposition of Nasal Sprays in an Idealized Nasal Inlet: Comparison with In Vivo Gamma Scintigraphy
John Chen
University of Alberta
Influence of Gender on the Disposition of OHet72 after Pulmonary Administration
Margaret Bourlon
University of Oklahoma Health Science Center
The Combined Effect of Valve and Spray Orifice Diameters on pMDI Plume Force
Benjamin Myatt
Kindeva Drug Delivery
A Continuous Process for Blending Dry Powders for Inhalation
Jamie Spahn
The University of Texas at Austin
The Application of Artificial Intelligence in Designing Dry Powder for Inhalation Using Thin-Film-Freezing Technology
Junhuang Jiang
The University of Texas at Austin
In Vitro Performance of a Pediatric Air-Jet DPI Delivering a Spray-Dried Antibiotic Formulation
Dale Farkas
Virginia Commonwealth University
Microfluidic Aerosol Generation: Development of a Next Generation Hand-Held Device for Aerosol Drug Delivery
Jason Brenker
Monash University

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A Physiologically-Based Pharmacokinetic Model to Estimate Absorption and Bioavailability of Corticosteroid Nasal Sprays
Jeffry Schroeter
Applied Research Associates
LG
Human Factor Studies on the Usability of an Aptar Bidose Nasal Drug Delivery Device
Laura Gillard and Benedicte Grosjean
Aptar Pharma
LGBL
Investigation of Leachables from pMDIs Containing Propellants HFA 134a, HFA 152a and HFO 1234ze
Laura Gillard and Bruno Lecorre
Aptar Pharma
JN
Physiologically Based Pharmacokinetic (PBPK) Modeling as a Strategic Tool to Predict Intranasal Drug Absorption
Jan Neelissen
Catalent
ASAS
Investigating the Impact of Electrostatics on Delivered Dose Uniformity for pMDIs
Anna Sipitanou and Adam Smith
Copley Scientific
RB
Pathophysiological Changes in a Clinically Relevant Large Animal Model of Experimental Chronic Obstructive Pulmonary Disease (COPD)
Rob Bischof
Federation University
AE
Why Won’t the Capsule Spin? Investigations into the Effects of Static and Powder Distribution on Non-Whirring Capsules In Dry Powder Inhalers
Avi Eliahu and Tom Pritsky
Genentech
JG
Plasma Technology: An Innovative and Sustainable pMDI Surface Treatment
Jacqueline Green
H&T Presspart
Assessing Delivered Dose of a Breath-Actuated Mesh Nebulizer: Breathing Simulator vs. NGI with Mixing Inlet Using Ipratropium Bromide
Edgar Hernan Cuevas Brun and Anne Tsai
HCmed Innovations
Aerosol Delivery Performance of Interferon Beta-1b with a Continuous Output Mode Mesh Nebulizer and a Breath-Actuated Mesh Nebulizer
Edgar Hernan Cuevas Brun
HCmed Innovations
NB
Factors Affecting the Performance of Lactose Carriers During Long-Term Storage
Nicholas Bungert
Kiel University
AS
The Use of Accelerated Stability Storage to Fast-Track the Development of a New Metered Dose Inhaler Incorporating the Greener Propellant HFA-152a
Alex Slowey and Benjamin Myatt
Kindeva Drug Delivery
Impact of Results Below Limit of Quantitation on MmCSRS Tool for Assessing Bioequivalence of Aerodynamic Particle Size Distributions
Stephen Stein
Kindeva Drug Delivery
GINA 2021 Guidelines and Considerations of Products Currently Available and Opportunities for Novel Combination Inhalers to Meet the Future Needs of Patients
Helen Derbyshire
Kindeva Drug Delivery
Using Dry Dispersion Laser Diffraction to Assess Strength and Dispersibility in Spheronized Agglomerate Formulations
Faustin Arevalo
Merck
CR
Screening of the Properties of Nasal Sprays Comprising Different Mucoadhesive Polymers Through a Design of Experiment Approach
Irene Rossi and Cristina Rey Blanes
Nanopharm, an Aptar Pharma Company
JH
Assessment of the Discriminatory Ability of SmartTrack® In Vitro Release Testing on Vilanterol Formulated in Dry Powder Inhalers
Irene Rossi and Jared Hall
Nanopharm, an Aptar Pharma Company
Storage Stability of a Nasal Spray Comprising a Novel Human Recombinant Antibody for SARS-CoV-2 Prophylactic Treatment
Irene Rossi and Antonia Zapata Del Bano
Nanopharm, an Aptar Pharma Company
LS
Optimizing the Osmolality of Intranasal Formulations Using a Predictive Statistical Model
Jag Shur and Luca Serratore
Nanopharm, an Aptar Pharma Company
ME
Aerosol Delivery and Neonates: Comparison of In Vitro Performances of Three Different Aerosol Delivery Techniques
Thierry Porée and Myriam Eckes
OptimHal-ProtecSom
Unsteady Aerosol Output Rate Measurements: Assessing the eFlow Nebulizer Aerosol Bolus
Stefan Seemann and Benjamin Heine
PARI Pharma
Development of a Novel Test Stand for the Measurement of Valved Holding Chambers with Face Masks
Stefan Seemann and Andrea Winzen
PARI Pharma
Towards More Realistic In Vitro Nebulizer Testing
Stefan Seemann and Uwe Schuschnig
PARI Pharma
Impact of Temperature and Relative Humidity on Spray Pattern Measurements of pMDIs: Reducing Measurement Bias
Christopher Gruenloh
PPD, part of Thermo Fisher Scientific
Effect of Critical Process Parameters and Cyclone Design on Aerosolization Properties and Yield of Erlotinib-Loaded Spray-Dried Cubosomal Powder for Lung Cancer Treatment
Akash Deep
Punjabi University
Simple and Efficient Delivery of Inhaled Soft Mist Aerosols Using the Hand-Held Pulmospray™
Lei Mao
Recipharm
Developing Spray Pattern and Plume Geometry Methods Incorporating Human Handling Factors: Multi-Dose Nasal Spray
Lei Mao
Recipharm
Effect of Inspiratory Flow Rate on Particle Size Distribution and In Silico Deposition Within the Respiratory Tract Using a Soft Mist Inhaler (SMI)
Bernhard Muellinger
Resyca
AT
Utilizing an ELN/LIMS to Minimize the Complexities Associated with Next Generation Impactor Testing of OINDPs
Adam Troxell
SciCord
Correlation Between Patient Handling Errors and In Vitro Performance of Spiriva® Handihaler®
Yannick Baschung
Solvias
A High Dose Dry Powder Formulation for an Unstable Antimicrobial Active Pharmaceutical Ingredient
Varsha Nair
The University of Texas at Austin
Design and Aerosol Performance of a Novel Dry Powder Nebulizer for High Dose Delivery
Hugh Smyth
The University of Texas at Austin
Aerosolizable Plasmid DNA Dry Powder Formulations Engineered by Thin-Film Freeze-Drying
Haiyue Xu
The University of Texas at Austin
Niclosamide Dry Powder for Inhalation Prepared by Thin Film Freezing Technology is Effective Against the COVID-19 Infection in the Golden Syrian Hamster Model
Miguel Orlando Jara Gonzalez
The University of Texas at Austin
HD
Aggregation of Lactoferrin Caused by Droplet Atomization Process Via Two-Fluid Nozzle: The Detrimental Effect of Air-Water Interfaces
Huy Dao
The University of Texas at Austin
AR
Effects of Processing Parameters for a Novel Continuous Manufacturing Method for Producing Dry Powder Inhalation Blends
Angela Ren
The University of Texas at Austin
Correlation of Specific Surface Area with Aerodynamic Performance and Physical Properties of Inhaled Nintedanib Powder Produced by Thin-Film Freeze-Drying
Tuangrat Praphawatvet
The University of Texas at Austin
What Part does the Tongue Play in the Transport of Inhaled Medications? An Experimental Study Using Adult Oropharyngeal Models
Jolyon Mitchell and Mark Nagel
Trudell Medical International
Paving the Way to pMDI Propellant Transition - A Laboratory Assessment of P152a-Based Formulation Performance used with a Commonly Referenced Spacer
Jason Suggett
Trudell Medical International
The Effects of Inhalation Flow Rate on Aerodynamic Particle Size Distribution of Commercial Solution and Suspension Metered Dose Inhalers
Abhinav Mohan
U.S. Food & Drug Administration
Effects of Formulation and Actuator Design on Spray Velocity of Mometasone Furoate Metered Dose Inhalers
Sneha Dhapare
U.S. Food & Drug Administration
Aerosol Deposition in Lung Airways Based on Force on Point Charge in Cylinder
Adel Hashish
United Arab Emirates University
AM
Intranasal Powder Administration of a Spray-Dried Tuberculosis Vaccine Candidate Characterized using the Alberta Idealized Nasal Inlet
Andrew Martin
University of Alberta
Spray Dried Porous Lipid Particles for Pulmonary Drug Delivery
Reinhard Vehring and Hui Wang
University of Alberta
Long-term Room Temperature Stability of a Spray-Dried Inhalable Tuberculosis Vaccine
Maximilian Aisenstat
University of Alberta
Predicting Aerosol Performance of pMDIs Containing Low-GWP Propellants using a One-Dimensional Thermofluid-Mechanic Model
Benjamin Thorne
University of Hertfordshire
Formulation and Characterization of a Dry Powder Inhaler Containing an ACE2 Miniprotein for SARS-CoV-2 Infection Inhibition
Stefania Glieca and Francesca Buttini
University of Parma
TH
Preparation of Coamorphous Ciprofloxacin Formulations with Enhanced Deposition Parameters for Dry Powder Inhalation
Thomas Hibbard
University of Reading
In Vitro Evaluation of Dry Powder Aerosol Delivery Efficiency to the Lungs of Preterm Infants Using Two Administration Approaches
Dale Farkas
Virginia Commonwealth University
RD
Development of a CFD-PK Nasal Spray Model with In Vivo Human Subject Validation
Rabijit Dutta
Virginia Commonwealth University
RD
Complete Airway CFD Simulations of DPI Aerosol Administration Using an Open-Source Freely Available Platform
Rabijit Dutta
Virginia Commonwealth University
Optimization and Characterization of a Tobramycin Excipient Enhanced Growth Spray-Dried Powder Formulation
Serena Bonasera and Michael Hindle
Virginia Commonwealth University
In Vitro Evaluation of Regional Drug Deposition in Nasal Airways of Children Using Realistic Anatomical Replicas
Amir Esmaeili
Virginia Commonwealth University
Assessing the Influences of Nasal Spray Administration Parameters on In Vitro Posterior Drug Delivery Using an Average Adult Nasal Airway Replica and Box-Behnken Experimental Design
Amir Esmaeili
Virginia Commonwealth University
Liposomal Dry Powder Aerosol Formulation of Ciprofloxacin: Effect of Sucrose and Mannitol on Aerosol Performance
Rudra Pangeni
Virginia Commonwealth University
Improving Nasal Olfactory Drug Targeting Using an Air-Jet DPI Device
Arun Kolanjiyil and Worth Longest
Virginia Commonwealth University
On the Importance of Liquid Motion in Nasal Spray Delivery
Arun Kolanjiyil and Worth Longest
Virginia Commonwealth University
Surfactant Powder Delivery from Infant Air-Jet Dry Powder Inhaler (DPI): Effect of Flow Rate and DPI Design
Mohammad Abdul Motalib Momin
Virginia Commonwealth University
Long-term Storage Stability of an Excipient Enhanced Growth (EEG) Pulmonary Surfactant Powder Formulation
Mohammad Abdul Motalib Momin
Virginia Commonwealth University
Dry Powder Aerosol Containing Muco-Inert Particles for Pulmonary Drug Delivery
Qingguo Xu
Virginia Commonwealth University
MO
Nebulization of Oxygen Nanodispersion in a Vibrating Mesh Nebulizer
Marcin Odziomek
Warsaw University of Technology
KD
Nebulization of Solutions Containing Guar Gum as a Viscosity Modifier of Natural Origin
Katarzyna Dobrowolska
Warsaw University of Technology
Vibrating Mesh Nebulizers with a Valved Inhalation Chamber for Increased Drug Delivery to the Lower Airways
Tomasz Sosnowski
Warsaw University of Technology
Implications of Ryegrass Pollen Exposure on Respiratory Cell Inflammatory Expression and Cellular Viscoelastic Properties
Aylin Cidem
Woolcock Institute of Medical Research
Aerosolization of Co-Spray Dried Dry Powder Inhalable Formulations of Diclofenac and Tobramycin: Comparison of Two and Three Fluid Spray Drier Nozzles
Nirmal Marasini
Woolcock Institute of Medical Research
In Vitro Characterization of Aerosolized Particles Using a Novel Cell-Impactor Integrated Model
Chun Yuen Jerry Wong
Woolcock Institute of Medical Research
The Effect of Lactose Quality Attributes on Predicted Inhaled Drug Deposition in Tiotropium Bromide DPI Formulations
Metin Karabulut
World Medicine
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