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Mimetikos PreludiumTM: A New Pharma-friendly Aerosol Drug Deposition Calculator

Olsson B, Bäckman P.

Respiratory Drug Delivery 2018. Volume 1, 2018: 103-112.

Abstract:

Mimetikos Preludium implements a number of literature algebraic lung deposition models and extends them to pharmaceutical aerosols in a comprehensive software that is available for licensing. Regional lung deposition is calculated based on known or assumed characteristics of the subject, the inhalation maneuver and the aerosol. Post-deposition, dissolution, mucociliary clearance (MCC), and absorption are simulated in parallel to provide the input function to a user-defined systemic disposition and clearance model.

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