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Patient Focused Device Design: Addressing Inhaler Technique and Improving Adherence

Lavorini F.

RDD Europe 2017. Volume 1, 2017: 1-10.

Abstract:

Asthma and chronic obstructive pulmonary disease (COPD) are common respiratory diseases with significant personal and worldwide economic impact. Inhalation therapy remains the cornerstone of treatment for these diseases since it allows the delivery of active molecules directly to the target site of action, while minimizing adverse side effects. Inhalers therefore play a crucial role in the effective management of patients with asthma and COPD, and inhaler choice is as important as that of the drug. Despite being pharmacologically efficacious, currently available inhaled drugs can have decreased real-life effectiveness due to a variety of factors including poor inhalation technique. Each device type has its own specifications regarding optimal use in terms of device handling and inhalation characteristics. Poor inhalation technique is associated with decreased treatment effectiveness. Proper education improves inhalation technique, adherence and outcomes/effectiveness, but has to be performed regularly and rigorously, including visual reinforcement of the patient’s ability to use the inhaler. Some testing devices are also available, as well as various training materials. All healthcare professionals caring for the patient can be involved, provided that they have been properly trained. To optimize treatment effectiveness, the choice of prescribed inhalation device(s) should be individualized, accounting for the specific characteristics of the patient, the disease, the device, and involved healthcare professionals.