Sponsor:    Vectura
Moderator: M. Geraldine Venthoye, Ph.D.

Inhalation of Therapeutic Monoclonal Antibodies for Respiratory Diseases: Challenges and Opportunities
Nathalie Heuzé-Vourc’h, Ph.D,
INSERM U1100, Université de Tours, Tours, France

Improving Asthma Rescue Treatment: Using Inhaled Corticosteroids to Enhance ß2-Adrenergic Bronchodilation
Adam Wanner, M.D.,
University of Miami, Miami, Florida, USA

Pharmacokinetic Behavior of Fluticasone Propionate and Salmeterol from Advair Diskus: The Consequences of Batch Variability
Elise Burmeister Getz, Ph.D.,
Oriel Therapeutics, Berkeley, California, USA

The Salford Lung Study: Rethinking Clinical Trial Design by Assessing Effectiveness in Clinical Practice
Ashley Woodcock, M.D.,
University of Manchester, Manchester, United Kingdom

Sponsor: Aptar Pharma
Moderator: Gerallt Williams, Ph.D.

The following companies each sponsored 60-minute interactive presentations on new technologies and services related to nasal and pulmonary drug delivery. Meeting participants could select and attend three of these sessions.

3M Drug Delivery Systems
The New Future - Introducing the Next Generation pMDI

Amcor
The Critical Role of Primary Packaging within the Qualification of Dry Powder Inhalers

Aptar Pharma & Propeller Health
Using Connected pMDIs to Monitor Inhaler Use and Drive Better Quality of Care

Capsugel
Engineered Particle Platform for Rapid Assessment of Inhaled Formulations: In Vitro and In Vivo Correlations

Centre of Postgraduate Medical Education (CMKP), Warsaw
Optimizing Dose Delivery of Nebulized Drugs

FLUIDDA
Functional Respiratory Imaging (FRI): Assessment of Lung Health to Optimize Respiratory Drug Delivery

H&T Presspart & Cohero Health
Smart Inhalers of the Future

Harro Höfliger Verpackungsmaschinen
Novel Inhaler for Controlled Pulmonary Delivery of Cannabis: Therapeutic and Technical Aspects

Hovione
Advanced Characterization and Design of Inhalable Formulations

Phillips-Medisize
Realizing the Benefits of Connected Health in Respiratory Drug Delivery

Proveris Scientific
Using a Novel Rapid Screening Technique to Streamline pMDI Formulation and Device Development

Qualicaps
Impact of Capsule Type on the Aerodynamic Performance of Dry Powder Formulations for Inhalation

Sponsor: H&T Presspart
Moderator: Stephen P. Stein, Ph.D.

Connecting Professionals and Patients:  How Technology can Support Asthma Self-Management
Hilary Pinnock, M.D.,
University of Edinburgh, Edinburgh, United Kingdom

Respiratory Acoustics: An Objective Assessment of Adherence to Inhalers in Patients with COPD
Richard W Costello, M.D.,
Royal College of Surgeons in Ireland, Dublin, Ireland

‘Track and Remind’: Can Connected Devices Improve Patient Adherence?
Garth Sutherland, M.Sc.,
Adherium, Auckland, New Zealand

Asthma Mobile Health Study: Engaging Patients in Asthma Self Management
Yu-Feng Y Chan, M.D. Ph.D.,
Icahn School of Medicine at Mount Sinai, New York, USA

Sponsor:     MEGGLE
Moderators: Joanne Peart, Ph.D., and Paul M. Young, Ph.D.

Five poster authors have been selected to summarize their work and answer questions during a fast-paced interactive podium session.

High-efficiency Delivery Of Aerosols Via An Infant Nasal Cannula
Susan Boc, B.Sc.
Virginia Commonwealth University, Richmond, Virginia, USA

Proof of Concept of the VITROCELL® Dry Powder Chamber: A New In Vitro Test System for the Controlled Deposition of Aerosol Formulations
Marius Hittinger, Ph.D.
PharmBio Tec, Saarbrücken, Germany

Validating a Realistic Physical Airway Model to Investigate In Vitro Drug Deposition, Dissolution, and Epithelial Transport of Orally Inhaled Products
Bao Huynh, B.Sc.
Woolcock Institute of Medical Research, Sydney, Australia

Comparison of Three Aqueous Aerosol Inhalation Devices for Delivering Anti-Tuberculosis Bacteriophage D29
Nicholas Carrigy, M.Eng.
University of Alberta, Edmonton, Alberta, Canada

Environmental Assessment of Metered Dose Inhaler Propellant: Potential For a Reduced Carbon Footprint Alternative
Adisa Azapagic, Ph.D.
University of Manchester, Manchester, United Kingdom

Presentation of VCU RDD Peter R. Byron Graduate Student Award

Sponsor:    Bespak
Moderator: John N. Pritchard, Ph.D.

New European Medical Device Regulations: Implications for Orally Inhaled and Nasal Drug Products
Maria E. Donawa, M.D.,
Donawa Lifescience Consulting, Rome, Italy

Licensing Medicines: Consequences of the UK “Brexit Vote” to leave the European Union
David Jefferys, M.D.,
Eisai Europe, Hatfield, United Kingdom

Sponsor: Chiesi Farmaceutici
Chairman and Advocate: Peter R. Byron, Ph.D.

Deposition Equivalence through DoE and Impaction Parameter Matching
Andrew R. Clark, Ph.D.,
Aerogen Pharma, San Mateo, California USA

Flow Rate Dependence of Powder Inhalers: The Importance of the Q-Index
Jeffry Weers, Ph.D.,
Scientific Consultant, Half Moon Bay, California, USA

Comparing Aerosol Capture in 8 Mouth-throat Models for a DPI, MDI and SMI
Dennis Sandell, Ph.D.,
S5 Consulting, Blentarp, Sweden

Old Throats for New: A Curve Ball Posed by New USP Product Monographs
Jolyon P. Mitchell, Ph.D. (Delivered via Teleconference),
Scientific Consultant, London, Ontario, Canada

Panel Discussion
Chairperson and Advocate: Peter R. Byron, Ph.D.
Virginia Commonwealth University, Richmond, Virginia, USA

Panel:
Elise Burmeister-Getz, Oriel Therapeutics
Andrew R. Clark, Aerogen Pharma
Jolyon P. Mitchell, Scientific Consultant
Dennis Sandell, S5 Consulting
Jeffry Weers, Novartis

Sponsor: Qualicaps
Moderator: Michael Hindle, Ph.D.

Acini-on-Chip: Novel In Vitro Assessment of Particle Dynamics and Deposition in the Deep Lung
Josué Sznitman, Ph.D.,
Technion - Israel Institute of Technology, Haifa, Israel

Using Phase Doppler Anemometry and High Speed Imaging to Analyze MDI Spray Plume Dynamics
Henk K. Versteeg, Ph.D.,
Loughborough University, Loughborough United Kingdom

Sponsor: Proveris Scientific
Moderator: Richard N. Dalby, Ph.D.

HFA-philicity: Excipient Screening for pMDI Formulations
Sandro R. P. Da Rocha, Ph.D.,
Virginia Commonwealth University, Richmond, Virginia, USA

Benchmarking Supercritical-CO₂ assisted Spray Drying with Conventional Spray Drying for the Manufacture of Inhalation Formulations
Márcio Temtem, Ph.D.,
Hovione FarmaCiencia, Loures, Portugal

Understanding Particle Formation Kinetics: Linking Device and Process with Particle Morphology and Product Performance
Reinhard Vehring, Ph.D.,
University of Alberta, Edmonton, Canada

Scientific and Regulatory Considerations on Particle Characterization and Specification Setting for Dry Powder Inhalers
Zhigang Sun, Ph.D. (Delivered via Teleconference),
Food and Drug Administration, Silver Spring, Maryland, USA